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- AgrigentoCity
Provincial capital on Sicily's southern coast, built where ancient Akragas stood: the archaeological area of the Valley of the Temples has been on UNESCO's World Heritage List since 1997 and the city was Italian Capital of Culture 2025. It has a local campus of the University of Palermo and hosts the Almond Blossom Festival every March.
Italy - CaltanissettaCity
Provincial capital in Sicily, with an Arab quarter (San Domenico) as its oldest core, the cathedral of Santa Maria La Nova and a state music conservatoire. It has a University of Palermo branch and the ASP's S. Elia hospital; the patron saint given by the municipality is San Michele Arcangelo.
Italy - CataniaCity
A city on the Ionian coast at the foot of Etna, rebuilt in Baroque style after the 1693 earthquake and part of the Val di Noto UNESCO site. It has Sicily's oldest university (1434) and a large STMicroelectronics site for power semiconductors. A metro and a railway around Etna; volcanic ash sometimes closes the airport.
Italy - EnnaCity
Provincial capital in Sicily, with the Castello di Lombardia, the Torre di Federico and the Rocca di Cerere among the places the municipality points to. It is home to the Libera Università degli Studi di Enna "Kore", a private non-state university founded in 2005, and to the ASP's Umberto I hospital with an emergency department open 24 hours.
Italy - MessinaCity
A city on the Strait, Sicily's gateway for those arriving from the mainland: ferries to Villa San Giovanni run day and night, Blu Jet fast ships also go to Reggio Calabria. Destroyed by the 1908 earthquake and tsunami and rebuilt. A university founded in 1548 with four campuses; in the city a tram and an ATM bus network that reaches the villages.
Italy - PalermoCity
Capital of the Sicilian Region and Italy's fifth city, over 600,000 residents, eight districts. An economy of public employment, retail, tourism, port and services; a large university. Rents below northern cities but rising in the historic centre. An island: you arrive by plane or ferry; very hot summers.
Italy - RagusaCity
Provincial capital of south-eastern Sicily whose historic centre, including Ibla, is part of the UNESCO site Late Baroque Towns of the Val di Noto (2002). The municipal area also includes Marina di Ragusa and the Castello di Donnafugata; the city hosts a Special Teaching Structure of the University of Catania with five degree courses.
Italy - SyracuseCity
A Greek city on the south-eastern Ionian coast, with its historic centre on the island of Ortigia; a UNESCO site since 2005 together with the Pantalica necropolis. The Greek theatre with INDA's season in May and June, the feast of Saint Lucy in December. To the north, the industrial hub of Augusta, Priolo and Melilli. The reference airport is Catania, reachable by train.
Italy - TrapaniCity
Provincial capital of western Sicily, squeezed between the sea and Mount Erice: the city grew around its port, salt and tuna fishing. It hosts a local campus of the University of Palermo, Trapani-Birgi airport run by Airgest, and urban buses run by ATM.
Italy - CagliariCity
Capital of the Autonomous Region of Sardinia, about 150,000 residents in the municipality and twice as many in the urban area. A city of administration, services, university, port and tourism, with the Poetto beach and the salt-pan park in town. The highest rents on the island; airport 7 km away by train; ferries to the mainland.
Italy - NuoroCity
A city in central Sardinia with a decentralised seat of the University of Sassari, the San Francesco hospital and the island's largest ethnographic museum, the Museo del Costume. The hamlet of Lollove and the Festa del Redentore round out the picture for newcomers and visitors.
Italy - OristanoCity
A Sardinian city known for Sa Sartiglia, a Carnival equestrian tournament run along via Vittorio Emanuele in front of the cathedral. It has the Antiquarium Arborense, a hospital (San Martino) and a seat of University of Cagliari and Sassari courses at Consorzio UNO.
Italy - SassariCity
Sardinia's second city by population and the historic reference point of the north of the island. Medieval historic centre with piazza Castello, piazza d'Italia, the Rosello Fountain and San Nicola cathedral; a royal university since 1617. The Candelieri festival (14 August, UNESCO-listed) and the Cavalcata Sarda (May). Platamona beach; Alghero airport 33 km away.
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